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The department of Medical Oncology includes the services to adult as well as paediatric patients, patients with endocrinologic disorders, Bone Marrow Transplant patients and services of psychiatry department. |
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| Bone Marrow Transplant and Research Unit |
| Bone Marrow Transplant Unit was established in August 1999, since then a number of transplants have been performed. The centre gets patients from states of Gujarat , Rajasthan, and Madhyapradesh. |
| The bone marrow transplant centre at GCRI is a 4 Bedded Transplant Centre with 8 step down beds. BMT Unit performs on an average one to two transplants in a month. Total 78 Hematopoietic stem cell transplants have been performed including 56 autologous, 21 allogenic& 1 matched unrelated umbilical cord till date. |
| The centre mainly focuses on conventional fully (6/6) HLA matched sibling allogenic for Thalassemia Major, Acute leukemia and Aplastic Anemia. Autologous Bone marrow transplantation performed mainly for Lymphomas(Hodgkin's and Non Hodgkin's) and Multiple Myeloma. Positive pressure HEPA filters has helped to achieve a very high success rate in the various types of diseases at our centre. Transplant Related Mortality (TRM) is comparable to any other institute in world. |
Average cost of Allogenic Transplant is 5-6 lakh( appx.) and 3-4 lakhs for Autologous transplant .
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| Allogenic Transplant - 21 |
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- AML - 10
- Thalassemia – 6
- Hurlers – 1
- ALL- 1
- CML – 2
- Aplastic Anemia-1
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Autologous Transplant – 56 |
- Multiple Myeloma - 20
- HD - 17
- NHL - 15
- GCT - 2
- Ewing 's sarcoma - 1
- Neuroblastoma - 1
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Umbilical cord blood transplant -1 |
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RESULTS & ANALYSIS:TRANSPLANT OUTCOME at GCRI |
AUTOLOGOUS |
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| Disease |
No. of pts |
CR&Well |
Remarks |
| Hodgkin's dis. |
17 |
12 |
60-70% survival
mean survival > 3 years --80 % pts |
| NHL |
15 |
06 |
2 pts completed 8yrs |
| Multiple Myeloma |
20 |
09 |
2 pts well after 8 yrs
mean survival >3 yrs in 60% of pts |
| Total |
52 |
27 |
>50% pts in CR & well |
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ALLOGENIC |
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Diagnosis |
No. of pts |
CR&Well |
Remarks |
| Thalassemia major
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06
01 |
03
01 |
HLA matched sibling-allo.
Unrelated HLA matched umbilical cord
Cord blood transplant
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| Acute myeloid leukemia
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10 |
03 |
Most of pts transplanted after 2nd remission. |
| CML-blastic crisis
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02 |
02 |
1 pt under Rx of chro.liver GVHD |
| Aplastic anemia |
01 |
01 |
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| Total |
20 |
10 |
50% pts are well |
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| For more information contact: |
| DR. SANDIP A. SHAH (M.D.) Hemato-oncologist |
Incharge Bone Marrow transplant unit.
Gujarat Cancer & Research Institute
Civil Hospital Campus, Ahmedabad. Gujarat.
M :9824041170, O79 -22688182
Email : sandip60@yahoo.com |
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